Tuktamyshov Rasikh, Jain Dhanpat, Ginsburg Philip M
Yale New Haven Hospital, 1450 Chapel Street, New Haven, CT, 06511, USA.
Department of Pathology, Yale University, 310 Cedar Street, New Haven, 208023, USA.
BMC Res Notes. 2015 May 7;8:188. doi: 10.1186/s13104-015-1139-3.
Merkel cell carcinoma is a rare and aggressive skin malignancy that arises from primary neural cells and has a tendency for local recurrence and regional lymph node metastases. There are only a few cases in the literature reporting metastases of Merkel cell carcinoma to the gastrointestinal tract.
We present a 70 year old Caucasian female with distant history of Merkel cell carcinoma who presented with iron-deficiency anemia. Colonoscopy performed later for the evaluation of anemia revealed 1 cm polyp in ascending colon which turned out to be the recurrence of Merkel cell carcinoma.
Metastatic Merkel cell carcinoma to the gastrointestinal tract or any other organ should be considered in patients with a history of Merkel cell carcinoma.
默克尔细胞癌是一种罕见且侵袭性强的皮肤恶性肿瘤，起源于原发性神经细胞，有局部复发和区域淋巴结转移的倾向。文献中仅有少数几例默克尔细胞癌转移至胃肠道的病例报道。
我们报告一名70岁的白种女性，有默克尔细胞癌病史，此次因缺铁性贫血就诊。后来为评估贫血而进行的结肠镜检查发现升结肠有一个1厘米的息肉，结果证实是默克尔细胞癌复发。
有默克尔细胞癌病史的患者应考虑默克尔细胞癌转移至胃肠道或其他任何器官的可能性。
