老年浆膜阳性胃癌的临床病理特征

Clinicopathologic characteristics of serosa-positive gastric carcinoma in elderly patients.

作者信息

Kim Ho Gun, Kang Hyo, Kim Dong Yi, Joo Jae Kyoon, Ryu Seong Yeob, Lee Jae Hyuk

机构信息

Division of Gastroenterologic Surgery, Department of Surgery, Chonnam National University Medical School, Gwangju, Korea.

出版信息

J Korean Surg Soc. 2011 Jul;81(1):19-24. doi: 10.4174/jkss.2011.81.1.19. Epub 2011 Jul 11.

DOI:10.4174/jkss.2011.81.1.19

PMID:22066096

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3204556/

Abstract

PURPOSE

The relationship between the prognosis and the age of patients with gastric carcinoma is controversial. This study examined the clinicopathologic features of elderly gastric carcinoma patients with serosal invasion.

METHODS

We reviewed the hospital records of 136 elderly gastric carcinoma patients with serosal invasion retrospectively to compare the clinicopathologic findings in the elderly (aged > 70 years) and young (aged < 36 years).

RESULTS

The 5-year survival rates of elderly and young patients with curative resection did not differ statistically (33.9% vs. 43.3%; P = 0.318). Multivariate analysis showed that two factors were independent, statistically significant parameters associated with survival: histologic type (risk ratio, 1.805; 95% confidence interval [CI], 1.041 to 3.132; P < 0.05) and operative curability (risk ratio, 2.506; 95% CI, 1.371 to 4.581; P < 0.01).

CONCLUSION

This study demonstrated that elderly gastric carcinoma patients with serosal invasion do not have a worse prognosis than young patients. The important prognostic factor was whether the patients underwent curative resection.

摘要

目的

胃癌患者的预后与年龄之间的关系存在争议。本研究探讨了伴有浆膜侵犯的老年胃癌患者的临床病理特征。

方法

我们回顾性分析了136例伴有浆膜侵犯的老年胃癌患者的医院记录，以比较老年（年龄>70岁）和年轻（年龄<36岁）患者的临床病理结果。

结果

接受根治性切除的老年和年轻患者的5年生存率在统计学上无差异（33.9%对43.3%；P = 0.318）。多因素分析显示，有两个因素是与生存相关的独立、具有统计学意义的参数：组织学类型（风险比，1.805；95%置信区间[CI]，1.041至3.132；P < 0.05）和手术可治愈性（风险比，2.506；95%CI，1.371至4.581；P < 0.01）。