King A J, McCabe J, Waldron M, Kerin M J, McGuire M, Given H F
Department of Surgery, University College Hospital, Galway, Republic of Ireland.
Br J Clin Pract. 1990 Jul;44(7):264-5.
The value of combined cytohistochemical examination in the diagnosis of malignant duodenal lesions was assessed in 78 patients with suspicious duodenal lesions seen at endoscopy. Cytological smears were taken using the direct-vision brushing technique and all were processed by the same experienced cytologist. Duodenal malignancy was confirmed histologically in four patients. Endoscopic biopsy was positive for malignancy in three of the patients and cytology was suspicious of malignant change in two patients and positive for malignant change in one patient. Cytology alone confirmed the diagnosis of malignancy in one patient. The cumulative diagnostic yield using both biopsy and cytology was 100%.
对78例在内镜检查中发现十二指肠病变可疑的患者，评估联合细胞组织化学检查在恶性十二指肠病变诊断中的价值。采用直视下刷检技术获取细胞学涂片，所有涂片均由同一位经验丰富的细胞学家处理。4例患者经组织学确诊为十二指肠恶性肿瘤。3例患者内镜活检显示恶性肿瘤阳性，2例患者细胞学检查怀疑有恶性改变，1例患者细胞学检查显示恶性改变阳性。仅细胞学检查确诊1例患者为恶性肿瘤。活检和细胞学检查的累积诊断率为100%。
