Venkataramana N K
Department of Neurosurgery, Advanced Neuroscience Institute, BGS Global Hospital, Bangalore, India.
J Pediatr Neurosci. 2011 Oct;6(Suppl 1):S31-40. doi: 10.4103/1817-1745.85707.
To review the clinical features and current understanding of spina bifida with an emphasis on the Indian Scenario. Selected articles and current English language texts were reviewed. The authors experience was also reviewed and analysed. Spina bifida is a common congenital anomaly encompassing a wide spectrum of neural tube defects.It is broadly classified as spina bifida aperta and occulta. With the prenatal screening, the incidence of aperta is gradually declining, whereas the detection of occulta has increased with the advent of magnetic resonance imaging. Over the years, the understanding of pathophysiology has made a significant changein the management of these anomalies. Early detection and complete correction can significantly reduce the neurological disability. This article is an overview of spina bifida with a special emphasis on Indian scenario.
回顾脊柱裂的临床特征及当前认识,重点关注印度的情况。对选定的文章和当前的英文文本进行了回顾。作者的经验也进行了回顾和分析。脊柱裂是一种常见的先天性异常,涵盖了广泛的神经管缺陷。它大致分为开放性脊柱裂和隐性脊柱裂。随着产前筛查的开展,开放性脊柱裂的发病率逐渐下降,而随着磁共振成像的出现,隐性脊柱裂的检出率有所增加。多年来,对病理生理学的认识在这些异常的管理方面带来了重大变化。早期发现和完全矫正可显著降低神经功能障碍。本文是对脊柱裂的概述,特别强调印度的情况。