胶原凝胶培养中肿瘤细胞间的通讯效率
Efficiency of communication between tumour cells in collagen gel cultures.
作者信息
Miller F R, McEachern D, Miller B E
机构信息
E. Walter Albachten Department of Immunology, Michigan Cancer Foundation, Detroit 48201.
出版信息
Br J Cancer. 1990 Sep;62(3):360-3. doi: 10.1038/bjc.1990.297.
Abstract
Mixtures of drug-resistant and drug-sensitive tumour cells growing in 3-dimensional boluses in collagen gel matrix are shown to be effectively coupled so that the response of the mixture is significantly influenced by a subpopulation making up only 1% of the total cells.
摘要
研究表明，在胶原蛋白凝胶基质中以三维团块形式生长的耐药性和药物敏感性肿瘤细胞混合物能够有效耦合，以至于仅占总细胞1%的亚群就能显著影响混合物的反应。
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Cancer Res. 1985 Sep;45(9):4200-5.
2
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Cancer Res. 1986 Jan;46(1):89-93.
3
Spontaneous fusion between metastatic mammary tumor subpopulations.转移性乳腺肿瘤亚群之间的自发融合。
J Cell Biochem. 1988 Feb;36(2):129-36. doi: 10.1002/jcb.240360204.
4
5
Size limit of molecules permeating the junctional membrane channels.透过连接膜通道的分子大小限制
Science. 1977 Jan 21;195(4275):294-6. doi: 10.1126/science.831276.
6
Sustained growth and three-dimensional organization of primary mammary tumor epithelial cells embedded in collagen gels.嵌入胶原凝胶中的原发性乳腺肿瘤上皮细胞的持续生长和三维组织
Proc Natl Acad Sci U S A. 1979 Jul;76(7):3401-5. doi: 10.1073/pnas.76.7.3401.
7
Junctional intercellular communication and the control of growth.连接部细胞间通讯与生长控制
Biochim Biophys Acta. 1979 Feb 4;560(1):1-65. doi: 10.1016/0304-419x(79)90002-7.
8
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Nature. 1978 Apr 6;272(5653):501-6. doi: 10.1038/272501a0.
9
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