Xiao Bo, Guo Shuzhong
Department of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an Shaanxi 710032, PR China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2011 Oct;25(10):1261-5.
To introduce the research progress in the immune of composite tissue allotransplantation.
The related articles were reviewed to summarize the immune characteristics, experimental developments, and clinical experiences of composite tissue allotransplantation. Results Composite allogeneic tissue is on the body surface, including the composition of the complex with high antigenicity. There are a lot of differences in the immune responses between composite tissue allotransplantation and organ transplantation, such as immunosuppressant protocol, rejection diagnosis, and chronic rejection.
In the next study, it is urgently needed to learn these experiences and to establish the special standard of composite tissue allotransplantation in induction of immune tolerance, local medication, and rejection diagnosis.
介绍复合组织同种异体移植免疫方面的研究进展。
查阅相关文献,总结复合组织同种异体移植的免疫特性、实验进展及临床经验。结果复合异体组织位于体表,包含具有高抗原性的复合体成分。复合组织同种异体移植与器官移植在免疫反应方面存在诸多差异,如免疫抑制剂方案、排斥反应诊断及慢性排斥反应等。
在未来研究中,迫切需要借鉴这些经验,建立复合组织同种异体移植在诱导免疫耐受、局部用药及排斥反应诊断方面的特殊标准。