Savić Dejan, Vojinović Slobodan, Spasić Mirjana, Perič Zoran, Lukić Stevo
Srp Arh Celok Lek. 2011 Sep-Oct;139(9-10):657-60. doi: 10.2298/sarh1110657s.
Syringomyelia is a cavitary extension inside the spinal cord which can be either symptomatic or congenitally-idiopathic. Syringomyelia during the course of the disease in patients presenting with clinically definite multiple sclerosis was described earlier. Syringomyelia in patients presenting with a clinically isolated syndrome suggestive of multiple sclerosis is unusual.
We present two patients presenting with demyelinating disease of the central nervous system with syringomyelia in the cervical and thoracic spinal cord. We did not find classical clinical signs of syringomyelia in our patients, but we disclosed syringomyelia incidentally during magnetic resonance exploration. Magnetic resonance exploration using the gadolinium contrast revealed the signs of active demyelinating lesions in the spinal cord in one patient but not in the other.
Syringomyelia in demyelinating disease of the central nervous system opens the question whether it is a coincidental finding or a part of clinical features of the disease. Differentiation of the significance of syringomyelia finding in these patients plays a role in the choice of treatment concept in such patients.
脊髓空洞症是脊髓内的空洞性扩展，可表现为症状性或先天性特发性。早期曾描述过临床确诊的多发性硬化症患者在疾病过程中出现的脊髓空洞症。表现为临床孤立综合征且提示多发性硬化症的患者出现脊髓空洞症并不常见。
我们报告了两名患有中枢神经系统脱髓鞘疾病且颈段和胸段脊髓有空洞症的患者。我们的患者未发现脊髓空洞症的典型临床体征，但在磁共振检查时偶然发现了脊髓空洞症。使用钆对比剂的磁共振检查显示，一名患者脊髓中有活动性脱髓鞘病变的迹象，而另一名患者则没有。
中枢神经系统脱髓鞘疾病中的脊髓空洞症引发了一个问题，即它是一个偶然发现还是该疾病临床特征的一部分。区分这些患者中脊髓空洞症发现的意义对这类患者治疗方案的选择具有重要作用。
