Department of Otorhinolaryngology and Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, South Korea.
Am J Otolaryngol. 2012 May-Jun;33(3):313-8. doi: 10.1016/j.amjoto.2011.10.001. Epub 2011 Nov 8.
Patients with Ramsay Hunt syndrome have a poorer prognosis than those with Bell palsy despite the use of various treatment modalities. We compared the clinical characteristics, treatment methods, and outcomes in patients with Ramsay Hunt syndrome and Bell palsy.
Patients with Ramsay Hunt syndrome were compared with patients with Bell palsy treated using oral steroids and with those treated with both steroids and an antiviral agent. Functional recovery of the facial nerve was scored according to the House-Brackmann grading system. Patients were followed up until recovery or for 3 months. Recovery rates in each group were assessed by age, sex, and initial and last House-Brackmann grade.
Compared with patients with Bell palsy, those with Ramsay Hunt syndrome were generally younger, had initially more severe facial palsy, and a lower recovery rate. Various factors including initial House-Brackmann grade, starting time to treatment, age, comorbid disease, electroneurography, and electromyography showed some correlations with prognosis in all groups. The addition of antiviral agents to an oral steroid regimen did not improve the recovery rate of patients with Bell palsy.
Patients with Ramsay Hunt syndrome have a poorer prognosis than do those with Bell palsy.
尽管采用了各种治疗方法，拉姆齐·亨特综合征（Ramsay Hunt syndrome）患者的预后仍比贝尔氏麻痹（Bell palsy）患者差。我们比较了拉姆齐·亨特综合征和贝尔氏麻痹患者的临床特征、治疗方法和结局。
将拉姆齐·亨特综合征患者与接受口服类固醇治疗的贝尔氏麻痹患者以及同时接受类固醇和抗病毒药物治疗的患者进行比较。面神经功能恢复根据 House-Brackmann 分级系统进行评分。对患者进行随访，直至恢复或随访 3 个月。通过年龄、性别以及初始和最后 House-Brackmann 分级评估每组的恢复率。
与贝尔氏麻痹患者相比，拉姆齐·亨特综合征患者通常年龄较小，面瘫初始程度更严重，恢复率较低。在所有组中，包括初始 House-Brackmann 分级、开始治疗时间、年龄、合并症、神经电图和肌电图在内的各种因素均与预后相关。在口服类固醇方案中加入抗病毒药物并不能提高贝尔氏麻痹患者的恢复率。
拉姆齐·亨特综合征患者的预后比贝尔氏麻痹患者差。
