CoRPS - Center of Research on Psychology in Somatic diseases, Tilburg University, Tilburg, The Netherlands.
Int J Cardiol. 2013 Jun 5;166(1):215-20. doi: 10.1016/j.ijcard.2011.10.092. Epub 2011 Nov 8.
The impact of ICD therapy on patient well being has typically focused on mean differences between groups, thereby neglecting changes within individuals. Using an intra-individual approach, we examined (i) the prevalence of implantable cardioverter defibrillator (ICD) patients maintaining their pre implantation level of psychological functioning at 12 months, and (ii) factors associated with deterioration in functioning.
Consecutively implanted ICD patients (n=332) completed a set of standardized and validated patient reported measures at baseline and at 12 months post implantation.
The majority of patients (72.8% to 81.7%) preserved their pre implantation level of psychological functioning 12 months post implantation. In adjusted analysis, ICD shock (all ps<.001) and Type D personality (all ps<.05) were independent predictors of deterioration in psychological functioning at 12 months across all domains, while baseline psychological status was associated with an improvement (all ps<.05). Patients with a primary prevention indication experienced a decrease in ICD concerns (p=.03) and anxiety (p=.006), and older patients (p=.04) a decrease in anxiety symptoms during the follow-up period. By contrast, patients with left ventricular dysfunction (p=.007) and atrial fibrillation (p=.02) were more likely to experience an increase in anxiety.
The majority of ICD patients maintained their pre implantation level of psychological functioning at 12 months. A subset of patients was at risk of poor psychological adaptation, attributable to ICD shocks, Type D personality, atrial fibrillation, and left ventricular dysfunction, while primary prevention indication and older age had a protective effect against deterioration in functioning.
ICD 治疗对患者健康的影响通常集中在组间的平均差异上,从而忽略了个体内部的变化。我们采用个体内方法,研究了 (i) 在 12 个月时,维持植入式心脏复律除颤器 (ICD) 患者心理功能术前水平的患者比例,以及 (ii) 与功能恶化相关的因素。
连续植入 ICD 的患者(n=332)在基线和植入后 12 个月时完成了一套标准化和验证的患者报告测量。
大多数患者(72.8%至 81.7%)在植入后 12 个月保持了术前的心理功能水平。在调整分析中,ICD 电击(所有 p<.001)和 D 型人格(所有 p<.05)是所有领域心理功能恶化的独立预测因素,而基线心理状态与改善相关(所有 p<.05)。有一级预防指征的患者 ICD 相关担忧(p=.03)和焦虑(p=.006)下降,年龄较大的患者(p=.04)在随访期间焦虑症状下降。相比之下,左心室功能障碍(p=.007)和心房颤动(p=.02)的患者更有可能出现焦虑增加。
大多数 ICD 患者在 12 个月时保持了术前的心理功能水平。一部分患者存在心理适应不良的风险,这归因于 ICD 电击、D 型人格、心房颤动和左心室功能障碍,而一级预防指征和年龄较大具有对功能恶化的保护作用。