Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, Israel.
Am J Obstet Gynecol. 2011 Sep;205(3):241.e1-6. doi: 10.1016/j.ajog.2011.06.013. Epub 2011 Jun 15.
To analyze pregnancy outcome in cases of isolated oligohydramnios at preterm.
A retrospective cohort study of singleton pregnancies diagnosed with isolated oligohydramnios at preterm (n = 108). Pregnancy outcome was compared with a matched control group of low-risk preterm pregnancies with normal levels of amniotic fluid in a 3:1 ratio (n = 324).
Pregnancies complicated by isolated oligohydramnios were characterized by a higher rate of preterm deliveries (26.9% vs 12.3%, P < .001), most of which were iatrogenic, and a higher rate of labor induction and cesarean delivery. Neonates with isolated oligohydramnios were characterized by a lower birthweight and a higher rate of neonatal morbidity. These differences were eliminated when the analysis was limited to the subgroup of pregnancies with isolated oligohydramnios that were managed expectantly and delivered spontaneously at term.
Adverse pregnancy outcome in cases of isolated oligohydramnios diagnosed at <37 weeks appears to be related to a considerable degree to iatrogenic prematurity.
分析早产时单纯性羊水过少的妊娠结局。
对 108 例在早产时被诊断为单纯性羊水过少的单胎妊娠进行回顾性队列研究。将其妊娠结局与羊水正常的低危早产妊娠（n=324）进行 3:1 配对对照。
单纯性羊水过少的妊娠其特点是早产率更高（26.9%比 12.3%，P<0.001），且大多为医源性早产，引产和剖宫产率也更高。单纯性羊水过少的新生儿其出生体重更低，且新生儿发病率更高。当分析仅限于期待治疗并在足月时自然分娩的单纯性羊水过少妊娠亚组时，这些差异则被消除。
在<37 周时诊断的单纯性羊水过少的不良妊娠结局在很大程度上与医源性早产有关。
