Fast V G, Pertsov A M
Biofizika. 1990 May-Jun;35(3):478-82.
The behavior of a vortex in rabbit myocardium with artificial inhomogeneity was studied using mapping technique. The inhomogeneity was created by perfusion of a part of the preparation with quinidine solution. Quinidine increased the refractory period of the myocardium and diminished the conduction velocity. It has been found that the vortex drifts along the border of the inhomogeneity because of the difference of refractory periods. The drift velocity was about 4 cm/s, which was five times less than the wave velocity. The direction of the drift was determined by the vector (----omega X----delta R), where ----omega is the angular velocity of vortex rotation, and ----delta R is a gradient of the refractory period.
采用标测技术研究了具有人工不均匀性的兔心肌中涡旋的行为。通过用奎尼丁溶液灌注标本的一部分来制造不均匀性。奎尼丁增加了心肌的不应期并降低了传导速度。已经发现,由于不应期的差异,涡旋沿着不均匀性的边界漂移。漂移速度约为4厘米/秒,比波速小五倍。漂移方向由矢量(----ω×----δR)确定,其中----ω是涡旋旋转的角速度,----δR是不应期的梯度。