Devulder B, Plouvier B
Sem Hop. 1979;55(7-8):360-6.
The T-lymphocyte is at the heart of the physiopathological mechanism of most dysimmunity affections. Furthermore, some cases of granulomatosis, the immediate consequence of macrophagic disorder, come within the framework of T-lymphocyte diseases, épicritical centre of the complex process of cellular immunity. By reference to new knowledges about various actions of T-lymphocytes and their interactions with lymphocytes B and macrophages, and by reference to classic pathologic findings of diseases of immunity, the author's propose a new classification of these diseases, suggesting therapeutic reasearch in consideration of effect of drugs, especially immunostimulant treatments, on the immune system.
T淋巴细胞是大多数免疫功能紊乱性疾病病理生理机制的核心。此外，某些肉芽肿病病例，即巨噬细胞功能障碍的直接后果，属于T淋巴细胞疾病范畴，是细胞免疫复杂过程的关键中心。参照有关T淋巴细胞的各种作用及其与B淋巴细胞和巨噬细胞相互作用的新知识，并参照免疫性疾病的经典病理发现，作者提出了这些疾病的新分类，建议在考虑药物，特别是免疫刺激治疗对免疫系统作用的基础上进行治疗研究。
