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Submembrane liprin-α1 clusters spatially localize insulin granule fusion.
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LRK-1/LRRK2 and AP-3 regulate trafficking of synaptic vesicle precursors through active zone protein SYD-2/Liprin-α.
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A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3.
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Presynaptic Cytomatrix Proteins.
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Synaptogenesis: unmasking molecular mechanisms using Caenorhabditis elegans.
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Liprins in oncogenic signaling and cancer cell adhesion.
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UNC-2 CaV2 Channel Localization at Presynaptic Active Zones Depends on UNC-10/RIM and SYD-2/Liprin-α in .
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Liprin-α-Mediated Assemblies and Their Roles in Synapse Formation.
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PTP-3 phosphatase promotes intramolecular folding of SYD-2 to inactivate kinesin-3 UNC-104 in neurons.
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The structure of the nervous system of the nematode Caenorhabditis elegans.
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Crystal structure of the central coiled-coil domain from human liprin-β2.
Biochemistry. 2011 May 10;50(18):3807-15. doi: 10.1021/bi200141e. Epub 2011 Apr 15.
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Three Drosophila liprins interact to control synapse formation.
J Neurosci. 2010 Nov 17;30(46):15358-68. doi: 10.1523/JNEUROSCI.1862-10.2010.
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A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila.
J Cell Biol. 2010 Feb 22;188(4):565-79. doi: 10.1083/jcb.200908055.
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Synaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans.
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Maturation of active zone assembly by Drosophila Bruchpilot.
J Cell Biol. 2009 Jul 13;186(1):129-45. doi: 10.1083/jcb.200812150.
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RSY-1 is a local inhibitor of presynaptic assembly in C. elegans.
Science. 2009 Mar 13;323(5920):1500-3. doi: 10.1126/science.1169025.
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Molecular mechanisms of presynaptic differentiation.
Annu Rev Cell Dev Biol. 2008;24:237-62. doi: 10.1146/annurev.cellbio.23.090506.123417.
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Liprin-alpha proteins: scaffold molecules for synapse maturation.
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