Jones Bridgette L
Department of Pediatrics, Children's Mercy Hospital and Clinics, USA.
Mo Med. 2011 Sep-Oct;108(5):361-5.
Personalized medicine includes the application of genomic information in predicting disease and therapeutic response to ultimately individualize patient care. Pharmacogenetics is key in achieving true personalized care. However, the clinical applicability of genetic testing to "everyday medicine" is yet to be realized. This paper will discuss areas in allergic/inflammatory disease that have been impacted by pharmacogenetic research and how this application may be brought from the "bench to the bedside."
个性化医疗包括应用基因组信息来预测疾病和治疗反应,最终实现患者护理的个体化。药物遗传学是实现真正个性化护理的关键。然而,基因检测在“日常医疗”中的临床适用性尚未实现。本文将讨论药物遗传学研究对过敏性/炎症性疾病领域的影响,以及如何将这种应用从“实验室带到临床”。