呼吸性窦性心律不齐减弱：人类甲状腺功能亢进症迷走神经活动受损的更多证据。
Depressed respiratory sinus arrhythmia: additional evidence for impairment of vagal activity in human hyperthyroidism.
作者信息
Maciel B C, Gallo Júnior J, Marin-Neto J A, Zanini-Maciel L M
机构信息
Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brasil.
出版信息
Braz J Med Biol Res. 1990;23(2):195-7.
The efferent activity of the parasympathetic component of the autonomic nervous system was evaluated by measuring the magnitude of the respiratory sinus arrhythmia in 3 female patients with hyperthyroidism (Basedow-Graves' disease) before and after treatment. The heart rate variations induced by the test increased in all patients after treatment of thyrotoxicosis (from 15 +/- 2.9 to 28.3 +/- 6.6 beats/min; mean +/- SEM) with propylthiouracil (600 mg/day). This result confirms our previous observations indicating an important and reversible impairment of the efferent vagal activity in human hyperthyroidism.
通过测量3例甲状腺功能亢进症（巴塞多-格雷夫斯病）女性患者治疗前后呼吸性窦性心律不齐的幅度，评估自主神经系统副交感神经成分的传出活动。用丙硫氧嘧啶（600毫克/天）治疗甲状腺毒症后，所有患者测试诱发的心率变化均增加（从15±2.9次/分钟增至28.3±6.6次/分钟；均值±标准误）。这一结果证实了我们之前的观察结果，表明人类甲状腺功能亢进症患者的传出迷走神经活动存在重要且可逆的损害。
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