Department of General and Digestive surgery, University Pierre & Marie-Curie, Paris VI, Hôpital Saint-Antoine, 184, rue du Faubourg-St-Antoine, 75012 Paris, France.
Clin Res Hepatol Gastroenterol. 2012 Feb;36(1):e12-6. doi: 10.1016/j.clinre.2011.09.006. Epub 2011 Nov 9.
Mucinous cystadenomas are tumors arising mostly from the ovaries and pancreas. They can also arise from the kidneys, lungs, liver and appendix, but are rarely seen in the mesocolon. Recently, they have been included in an updated classification of mesenteric cysts and cystic tumors. The WHO classification (ICD 10) divides them into three subcategories according to their malignant behavior.
This report of two cases of mucinous cystadenoma of the mesocolon discusses the diagnostic and therapeutic modalities as well as the pathophysiological pathway(s) of development of these neoplasms.
The diagnosis of mucinous cystadenomas of the mesocolon is challenging due to the absence of specific clinical, biological and radiological features, and is often made during or after laparotomy. Preoperative biopsy is not useful and may even lead to misdiagnosis or peritoneal spillage. Surgery is the only curative treatment, but the modalities of resection are still a subject of debate.
黏液性囊腺瘤主要起源于卵巢和胰腺。它们也可能起源于肾脏、肺、肝和阑尾,但在肠系膜中很少见。最近,它们被纳入肠系膜囊肿和囊性肿瘤的最新分类中。世界卫生组织(WHO)分类(ICD-10)根据其恶性行为将其分为三个亚类。
本报告讨论了两个肠系膜黏液性囊腺瘤病例,讨论了这些肿瘤的诊断和治疗方法以及发病的病理生理途径。
由于缺乏特定的临床、生物学和影像学特征,肠系膜黏液性囊腺瘤的诊断具有挑战性,通常在剖腹手术期间或之后进行。术前活检没有用处,甚至可能导致误诊或腹膜播散。手术是唯一的治愈性治疗方法,但切除方式仍存在争议。