Hara Takashi, Kawashima Hideaki, Ishigooka Masahiro, Kashiyama Motoya, Takanashi Setsuji, Yamazaki Sayuki, Hosokawa Yoshio
Department of Surgery, Kin-I-Kyo Chuou Hospital, 2-15-1, 10-jo, Fushiko, Higashi-ku, Sapporo, Hokkaido 007-8505, Japan.
Surg Today. 2002;32(11):965-9. doi: 10.1007/s005950200193.
This study was conducted to clarify the clinicopathologic characteristics relevant to the specific diagnosis of mucinous cystic tumors of the pancreas.
We retrospectively reviewed the clinical features and histopathologic findings of five patients who underwent curative resection for mucinous cystic tumors of the pancreas at our hospital between 1975 and 2000.
All five patients were women, ranging in age from 36 to 69 years, and the tumors were located in the pancreatic body and tail. Histopathologically, three tumors were mucinous cystadenomas and two were mucinous cystadenocarcinomas. All five tumors had ovarian-type stroma, and stromal luteinization was found in the three adenomas. These tumors were classified into two groups according to whether the epithelial lining was endocervical or intestinal. All tumors were spherical and multilocular with a fibrous pseudocapsule. On T1-weighted magnetic resonance images, mucinous cystadenomas with watery mucin showed low signal intensity, but mucinous cystadenocarcinomas with gelatinous mucin or hemorrhagic contents demonstrated high signal intensity.
Signal intensity on T1-weighted magnetic resonance images provides highly useful diagnostic information on mucinous cystic tumors of the pancreas. Furthermore, tumors may be classified into two groups according to the type of epithelial lining.
本研究旨在阐明与胰腺黏液性囊性肿瘤特定诊断相关的临床病理特征。
我们回顾性分析了1975年至2000年间在我院接受胰腺黏液性囊性肿瘤根治性切除的5例患者的临床特征和组织病理学表现。
所有5例患者均为女性，年龄在36至69岁之间，肿瘤位于胰体和胰尾。组织病理学上，3例为黏液性囊腺瘤，2例为黏液性囊腺癌。所有5例肿瘤均有卵巢型间质，3例腺瘤中发现间质黄素化。根据上皮内衬是宫颈内膜型还是肠型，这些肿瘤分为两组。所有肿瘤均为球形、多房性，有纤维性假包膜。在T1加权磁共振图像上，含有水样黏液的黏液性囊腺瘤表现为低信号强度，但含有胶冻样黏液或出血内容物的黏液性囊腺癌表现为高信号强度。
T1加权磁共振图像上的信号强度为胰腺黏液性囊性肿瘤提供了非常有用的诊断信息。此外，肿瘤可根据上皮内衬类型分为两组。
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