Divéky L, Handzo I, Vierik J, Krizko M, Suska P, Vozár J, Bella J, Valúch J, Pohlodek K
Katedry gynekológie a pôrodníctva II LFUK v Bratislave.
Bratisl Lek Listy. 1990 Jul;91(7):539-50.
Lipids represent one of the basic components of each cellular and subcellular membrane of the myometrium and their fluidity has a strong influence upon membrane function. Human myometrium was obtained at cesarean sections. Lipids were separated by one-dimensional thin layer chromatography. The chromatoplates were determined on the densitometer Shimadzu CS 930. Lipid profile of the myometrium was studied before the 37th week of pregnancy, at term without contractile activity, further during at term labor with normal contractile activity and at failure of myometrial contractility. Analysis of the obtained data showed changes in lipid fluidity, namely a decrease before the 37th week of pregnancy and at failure of myometrial contractions during at term labor. The decrease of fluidity was caused by a higher content of total cholesterol and a lower content of total phospholipids in the myometrium.
脂质是子宫肌层每个细胞和亚细胞膜的基本成分之一，其流动性对膜功能有很大影响。人类子宫肌层取自剖宫产手术。脂质通过一维薄层色谱法分离。在岛津CS 930密度计上测定色谱板。研究了妊娠37周前、足月无收缩活动时、足月有正常收缩活动的分娩过程中以及子宫肌层收缩功能衰竭时子宫肌层的脂质谱。对所得数据的分析表明脂质流动性发生了变化，即在妊娠37周前以及足月分娩时子宫肌层收缩功能衰竭时降低。流动性降低是由于子宫肌层中总胆固醇含量较高和总磷脂含量较低所致。
