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[分娩前及分娩过程中不同收缩阶段人子宫肌层中的磷脂]

[Phospholipids in the human myometrium in various stages of contraction before and during labor].

作者信息

Divéky L, Handzo I, Krizko M, Suska P, Vozár I, Bella J, Valúch J, Turecký L, Pohlodek K

机构信息

Klinika gynekológie a pôrodníctva II LFUK, Bratislava.

出版信息

Bratisl Lek Listy. 1990 Sep;91(9):720-6.

PMID:2224557
Abstract

A detailed analysis of the myometrium showed that the physical state of phospholipids--fluidity--depends on the ratio of their individual components and changes in relation to the state of contractile activity. The results indicate that before term of labor changes in the fluidity of myometrial phospholipids as well as increased availability of arachidonic acid for prostaglandin synthesis can induce preterm onset of contractile activity. Possibilities of affecting these mechanisms, which belong to the many potential factors inducing preterm labor, are discussed.

摘要

对子宫肌层的详细分析表明,磷脂的物理状态——流动性——取决于其各个成分的比例,并随着收缩活动状态的变化而变化。结果表明,在分娩前,子宫肌层磷脂流动性的变化以及花生四烯酸用于前列腺素合成的可用性增加,可诱导收缩活动早产。本文讨论了影响这些机制的可能性,这些机制属于许多诱发早产的潜在因素。

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