Axe Santé des Populations et Environnement, Centre de Recherche du CHUQ, 2875 Boulevard Laurier, Québec G1V 2M2, Canada.
Environ Health. 2011 Nov 13;10:99. doi: 10.1186/1476-069X-10-99.
Populations which diet is rich in seafood are highly exposed to contaminants such as mercury, which could affect cardiovascular risk factors
To assess the associations between mercury and blood pressure (BP), resting heart rate (HR) and HR variability (HRV) among French Polynesians
Data were collected among 180 adults (≥ 18 years) and 101 teenagers (12-17 years). HRV was measured using a two-hour ambulatory electrocardiogram (Holter) and BP was measured using a standardized protocol. The association between mercury and HRV and BP parameters was studied using analysis of variance (ANOVA) and analysis of covariance (ANCOVA) RESULTS: Among teenagers, the high frequency (HF) decreased between the 2nd and 3rd tertile (380 vs. 204 ms2, p = 0.03) and a similar pattern was observed for the square root of the mean squared differences of successive R-R intervals (rMSSD) (43 vs. 30 ms, p = 0.005) after adjusting for confounders. In addition, the ratio low/high frequency (LF/HF) increased between the 2nd and 3rd tertile (2.3 vs. 3.0, p = 0.04). Among adults, the standard deviation of R-R intervals (SDNN) tended to decrease between the 1st and 2nd tertile (84 vs. 75 ms, p = 0.069) after adjusting for confounders. Furthermore, diastolic BP tended to increase between the 2nd and 3rd tertile (86 vs. 91 mm Hg, p = 0.09). No significant difference was observed in resting HR or pulse pressure (PP) CONCLUSIONS: Mercury was associated with decreased HRV among French Polynesian teenagers while no significant association was observed with resting HR, BP, or PP among teenagers or adults.
饮食富含海鲜的人群会接触到大量的汞等污染物，这可能会影响心血管风险因素。
评估法属波利尼西亚人群中汞与血压（BP）、静息心率（HR）和心率变异性（HRV）之间的关系。
数据收集于 180 名成年人（≥18 岁）和 101 名青少年（12-17 岁）。使用两小时动态心电图（Holter）测量 HRV，使用标准化方案测量 BP。使用方差分析（ANOVA）和协方差分析（ANCOVA）研究汞与 HRV 和 BP 参数之间的关系。
在青少年中，高频（HF）在第 2 和第 3 tertile 之间降低（380 对 204 ms2，p = 0.03），在调整混杂因素后，平方均差的均方根差异（rMSSD）也表现出类似的模式（43 对 30 ms，p = 0.005）。此外，低频/高频（LF/HF）比值在第 2 和第 3 tertile 之间增加（2.3 对 3.0，p = 0.04）。在成年人中，在调整混杂因素后，RR 间期标准差（SDNN）在第 1 和第 2 tertile 之间趋于降低（84 对 75 ms，p = 0.069）。此外，舒张压在第 2 和第 3 tertile 之间趋于升高（86 对 91 mm Hg，p = 0.09）。静息 HR 或脉压（PP）无显著差异。
在法属波利尼西亚青少年中，汞与 HRV 降低有关，而在青少年或成年人中，汞与静息 HR、BP 或 PP 无显著关联。
