Kooh S W, Binet A
Department of Paediatrics, Hospital for Sick Children, Toronto, Ont.
CMAJ. 1990 Sep 15;143(6):509-12.
To our knowledge apnea in infants has not been associated with hypercalcemia. We describe seven hypercalcemic infants aged 2 days to 3 months who had presented with apnea; six of the seven were otherwise healthy. The apneic attacks were brief, and normal breathing was restored spontaneously or after tactile stimulation. The attacks stopped and the apnea monitoring was discontinued when the children were 1 month to 2 years of age. The only abnormal finding common to all of the patients was hypercalcemia. Idiopathic infantile hypercalcemia was diagnosed in six of the patients and familial benign hypercalcemia in one. Our findings suggest that determination of the plasma calcium level be included in the investigation of apnea in infancy.
据我们所知，婴儿呼吸暂停与高钙血症并无关联。我们描述了7名年龄在2天至3个月的高钙血症婴儿，他们均出现了呼吸暂停症状；其中7名婴儿中有6名在其他方面健康。呼吸暂停发作短暂，呼吸可自行恢复正常，或经触觉刺激后恢复。当患儿年龄在1个月至2岁时，发作停止，呼吸暂停监测也随之终止。所有患者唯一的共同异常发现是高钙血症。6名患者被诊断为特发性婴儿高钙血症，1名患者被诊断为家族性良性高钙血症。我们的研究结果表明，婴儿呼吸暂停的调查应包括血浆钙水平的测定。
