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乙型肝炎病毒相关肝硬化中由肝细胞腺瘤发生的肝细胞癌。

Hepatocellular carcinoma arising from hepatocellular adenoma in a hepatitis B virus-associated cirrhotic liver.

机构信息

Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

出版信息

Clin Radiol. 2012 Apr;67(4):329-33. doi: 10.1016/j.crad.2011.09.003. Epub 2011 Nov 12.

DOI:10.1016/j.crad.2011.09.003
PMID:22079485
Abstract

Hepatocellular adenoma (HCA) is a rare, benign proliferation of hepatocytes that occurs mostly in a normal liver and in extreme rare cases, occurs in a cirrhotic liver. Hepatocellular carcinomas (HCC) arising within HCA through malignant transformation is rare. The specific incidence and mechanism of malignant transformation has not been established, but the long term use of oral contraceptives is considered a causative agent. We report a case of HCC arising from HCA detected in a hepatitis B-related cirrhotic liver with serial radiologic images.

摘要

肝细胞腺瘤(HCA)是一种罕见的良性肝细胞增生,主要发生在正常肝脏中,极少数情况下发生在肝硬化肝脏中。通过恶性转化在 HCA 中发生的肝细胞癌(HCC)很少见。恶性转化的确切发病率和机制尚未确定,但长期使用口服避孕药被认为是一个致病因素。我们报告了一例在乙型肝炎相关肝硬化肝脏中通过连续影像学图像检测到的源自 HCA 的 HCC。

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