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分析番茄轻斑驳病毒基因组表明,它是 Ipomovirus 属(Potyviridae 科)中最具差异的成员。

Analysis of the tomato mild mottle virus genome indicates that it is the most divergent member of the genus Ipomovirus (family Potyviridae).

机构信息

German Collection of Microorganisms and Cell Cultures, DSMZ, Brunswick, Germany.

出版信息

Arch Virol. 2012 Feb;157(2):353-7. doi: 10.1007/s00705-011-1167-9. Epub 2011 Nov 12.

DOI:10.1007/s00705-011-1167-9
PMID:22080188
Abstract

The complete genome of a tomato mild mottle virus (ToMMV) isolate was analysed, and some biological features were characterized. The ssRNA genome of ToMMV from Ethiopia encompasses 9283 nucleotides (excluding the 3' poly(A) tail) and encodes a polyprotein of 3011 amino acids. Phylogenetic and pairwise comparisons with other members of the family Potyviridae revealed that ToMMV is the most divergent member of the genus Ipomovirus, with a genome organization similar to that of members of the species Sweet potato mild mottle virus, the type species of the genus. In contrast to earlier reports, ToMMV isolates from Yemen and Ethiopia were not transmitted by the aphid Myzus persicae, but they were transmitted very erratically by the whitefly Bemisia tabaci. A comparison of the 3'-proximal sequences of different isolates provided evidence for geographically associated genetic variation.

摘要

对一个番茄轻斑驳病毒(ToMMV)分离株的全基因组进行了分析,并对其部分生物学特性进行了研究。来自埃塞俄比亚的 ToMMV 的 ssRNA 基因组包含 9283 个核苷酸(不包括 3' 多聚(A)尾),并编码一个由 3011 个氨基酸组成的多聚蛋白。与其他壶菌科成员的系统发育和成对比较表明,ToMMV 是 Ipomovirus 属中最具差异的成员,其基因组组织与该属的甜薯轻斑驳病毒种成员相似。与早期的报告相反,来自也门和埃塞俄比亚的 ToMMV 分离株不能被蚜虫桃蚜传播,但它们可以被粉虱烟粉虱非常不稳定地传播。不同分离株的 3'-近端序列比较为地理相关的遗传变异提供了证据。

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An atypical RNA silencing suppression strategy provides a snapshot of the evolution of sweet potato-infecting potyviruses.一种非典型的 RNA 沉默抑制策略提供了甘薯感染马铃薯 Y 病毒进化的一个快照。
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