Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology, Wuhan, Hubei 430074, PR China.
Analyst. 2012 Jan 7;137(1):49-58. doi: 10.1039/c1an15738h. Epub 2011 Nov 14.
Due to the significance of hydrogen peroxide (H(2)O(2)) in biological systems and its practical applications, the development of efficient electrochemical H(2)O(2) sensors holds a special attraction for researchers. Various materials such as Prussian blue (PB), heme proteins, carbon nanotubes (CNTs) and transition metals have been applied to the construction of H(2)O(2) sensors. In this article, the electrocatalytic H(2)O(2) determinations are mainly focused on because they can provide a superior sensing performance over non-electrocatalytic ones. The synergetic effect between nanotechnology and electrochemical H(2)O(2) determination is also highlighted in various aspects. In addition, some recent progress for in vivo H(2)O(2) measurements is also presented. Finally, the future prospects for more efficient H(2)O(2) sensing are discussed.
由于过氧化氢(H₂O₂)在生物系统中的重要性及其实际应用,高效电化学 H₂O₂传感器的开发引起了研究人员的特别关注。各种材料,如普鲁士蓝(PB)、血红素蛋白、碳纳米管(CNTs)和过渡金属,已被应用于 H₂O₂传感器的构建。在本文中,主要关注电催化 H₂O₂测定,因为它们可以提供优于非电催化测定的传感性能。纳米技术与电化学 H₂O₂测定的协同作用也在各个方面得到了强调。此外,还介绍了一些用于体内 H₂O₂测量的最新进展。最后,讨论了更高效的 H₂O₂传感的未来前景。