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异物相关性眶肌炎 1 例

A unique case of foreign-body associated orbital myositis.

机构信息

Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas 77030, USA.

出版信息

Ophthalmic Plast Reconstr Surg. 2012 Jul-Aug;28(4):e80-2. doi: 10.1097/IOP.0b013e31822ddf9b.

Abstract

A 50-year-old woman presented with a 2-week history of diplopia and right-sided orbital pain with eye movement. Examination revealed an edematous, ptotic right upper eyelid with conjunctival hyperemia, proptosis, and significant limitation to upward and downward ductions on the right. MRI was significant for a homogeneously enhancing lesion within the superior rectus muscle. A laboratory evaluation seeking an infectious, inflammatory, or autoimmune process was nonrevealing. A diagnosis of orbital myositis was made, and the patient experienced significant improvement with oral corticosteroids. The patient's symptoms, however, recurred after attempts at a slow taper of the corticosteroids. An orbital biopsy of the lesion revealed fibroadipose tissue containing irregularly shaped yellow-white deposits birefringent under polarized light, suggestive of silica crystals. The patient denied any history of trauma or prior surgery. An intraorbital triamcinolone injection to the superior orbit allowed resolution of symptoms and a successful taper off systemic corticosteroids.

摘要

一位 50 岁女性因复视和右侧眼眶疼痛伴眼球运动受限就诊,病史为 2 周。检查发现右上眼睑水肿、下垂,伴有结膜充血、眼球突出和明显的眼球上、下运动受限。MRI 显示上直肌内均匀强化病变。实验室检查未发现感染、炎症或自身免疫过程。诊断为眼眶肌炎,患者口服皮质类固醇后症状显著改善。然而,在尝试缓慢减少皮质类固醇剂量后,患者的症状再次出现。病变的眼眶活检显示纤维脂肪组织,其中含有在偏振光下呈双折射的不规则形状的黄白色沉积物,提示为二氧化硅晶体。患者否认有外伤或既往手术史。对眼眶内上象限进行曲安奈德注射,使症状得以缓解,并成功减少全身皮质类固醇的用量。

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