Second Department of Radiation Oncology, "Saint Savvas" Anticancer Institute of Athens, Athens, Greece.
Clin Transl Oncol. 2011 Nov;13(11):793-7. doi: 10.1007/s12094-011-0735-5.
Ameloblastoma is known as a benign, slow-growing, rare, odontogenic neoplasm. The solid/multicystic, the unicystic with a fibrous connective-tissue capsule and the peripheral ameloblastoma represent the three well distinguished clinical types of ameloblastoma. Surgical resection with an attempt to achieve adequate free margins constitutes a well documented and accepted treatment modality. Controversies exist, however, with regard to the extent of operative intervention. Patients with inadequate or positive surgical margins or unresectable lesions can be treated with radiation or combined radiation and chemotherapy. The authors present a review of this sparse disease focusing on the special role and efficacy of radiation therapy in its management.
成釉细胞瘤被认为是一种良性、生长缓慢、罕见的牙源性肿瘤。实性/多囊型、含纤维结缔组织囊的单囊型和外周型成釉细胞瘤代表了成釉细胞瘤三种截然不同的临床类型。手术切除并尽可能达到充分的游离缘是一种有充分文献记载并被广泛接受的治疗方法。然而,对于手术干预的范围仍存在争议。对于手术切缘不足或阳性或无法切除的病变的患者,可以采用放疗或放化疗联合治疗。作者对这种罕见疾病进行了回顾,重点介绍了放射治疗在其治疗中的特殊作用和疗效。