Bertossi Dario, Favero Vittorio, Albanese Massimo, De-Santis Daniele, Martano Manuela, Padovano-di-Leva Antongiulio, De-Florio Iride, Nocini Pier F, Lo-Muzio Lorenzo
Unit of Dentistry and Maxillo-Facial Surgery, University of Verona, Italy.
Department of Veterinary Medicine and Animal Productions, University of Naples, Italy.
J Clin Exp Dent. 2014 Apr 1;6(2):e180-4. doi: 10.4317/jced.51124. eCollection 2014 Apr.
According to the 2005 histological classification of odontogenic neoplasms by the World Health Organization, ameloblastoma is a benign, locally invasive epithelial odontogenic tumor of putative enamel organ origin. There are four distinct subgroups in which this neoplasm can be gathered: the solid/multicystic type, the unicystic type, the desmoplastic and the peripheral type. Peripheral ameloblastoma is believed to be the rarest subgroup, making up for 2 to 10% of all ameloblastomas. From its first description by Kuru in 1911 to date, less than 200 cases of PA have been described in literature. PAs commonly affect the mandible, in the maxilla the most common location is the soft palatal tissue of the tuberosity area. The present report discusses a rare case of PA aroused in the gingiva of upper jaw in a 64-year-old woman. The treatment of the lesion and its immunohistochemical phenotype are described. A review of the literature is also performed, focusing on the epidemiological and pathological aspects of the lesions and their implications on the therapy. Key words:Peripheral ameloblastoma, upper gingiva, ameloblastoma.
根据世界卫生组织2005年牙源性肿瘤组织学分类,成釉细胞瘤是一种起源于推测的成釉器的良性、局部浸润性上皮性牙源性肿瘤。该肿瘤可分为四个不同的亚组:实性/多囊型、单囊型、促结缔组织增生型和外周型。外周型成釉细胞瘤被认为是最罕见的亚组,占所有成釉细胞瘤的2%至10%。从1911年库鲁首次描述至今,文献中报道的外周型成釉细胞瘤病例不到200例。外周型成釉细胞瘤通常累及下颌骨,在上颌骨中最常见的部位是结节区的软腭组织。本报告讨论了一名64岁女性上颌牙龈发生的罕见外周型成釉细胞瘤病例。描述了该病变的治疗及其免疫组化表型。还进行了文献综述,重点关注病变的流行病学和病理学方面及其对治疗的影响。关键词:外周型成釉细胞瘤;上颌牙龈;成釉细胞瘤