Department of Obstetrics and Gynecology, Marian Medical Center, Santa Maria, CA, USA.
Am J Obstet Gynecol. 2011 Oct;205(4):368.e1-8. doi: 10.1016/j.ajog.2011.06.084. Epub 2011 Jun 29.
The purpose of this study was to assess the effectiveness of instituting a comprehensive protocol for the treatment of maternal hemorrhage.
The protocol was separated into 4 stages, designated 0-3, based on the degree of blood loss and the patient response to interventions. Key components included admission risk assessment, measurement of blood loss, early but limited use of uterotonic agents, early presence of obstetrical and anesthesia staff, and transfusion with fixed ratios of blood products. Data were collected retrospectively and prospectively relative to the start of the protocol.
We noted a significant shift toward resolution of maternal bleeding at an earlier stage (P < .01), use of fewer blood products (P < .01), and a 64% reduction in the rate of disseminated intravascular coagulation. In addition, there were significant improvements in staff and physician perceptions of patient safety (P < .01).
Comprehensive maternal hemorrhage treatment protocols improve patient safety and reduce utilization of blood products.
本研究旨在评估实施全面的产妇出血治疗方案的效果。
该方案根据失血量和患者对干预措施的反应分为 4 个阶段,分别标记为 0-3 期。关键组成部分包括入院风险评估、出血量测量、早期但有限地使用宫缩剂、产科和麻醉人员的早期到场,以及按照固定比例输注血液制品。数据是根据方案启动时间进行回顾性和前瞻性收集的。
我们注意到产妇出血在更早阶段得到解决的比例显著增加(P <.01),血液制品的使用减少(P <.01),弥漫性血管内凝血的发生率降低了 64%。此外,工作人员和医生对患者安全的认知显著提高(P <.01)。
全面的产妇出血治疗方案可提高患者安全性并减少血液制品的使用。