Hama Mineyuki, Komatsu Yoshimichi, Hachiya Tsutomu
Dept. of Respiratory, Japanese Red Cross Society, Japan.
Gan To Kagaku Ryoho. 2011 Nov;38(11):1877-9.
A 63-year-old man was admitted to our hospital because of dyspnea. Chest computed tomographic(CT)scans showed right pleural effusion. He was diagnosed with adenocarcinoma of the lung(cTXN2M1a, stage IV). Although combination chemotherapy with 80 mg/m / 2 cisplatin(CDDP)and 60 mg/m2 docetaxel hydrate(DOC)was performed for 3 courses, the pleural effusion increased. As he had a progressive disease, his chemotherapy was changed to a new combination of AUC5 carboplatin(CBDCA), 200mg/m / 2 paclitaxel(PTX)and 15 mg/kg bevacizumab. After 2 courses, the pleural effusion dramatically decreased. During 6-month follow-up after the initial consultation, there has been no exacerbation.
一名63岁男性因呼吸困难入住我院。胸部计算机断层扫描（CT）显示右侧胸腔积液。他被诊断为肺癌（cTXN2M1a，IV期）。尽管采用80mg/m²顺铂（CDDP）和60mg/m²多西他赛水合物（DOC）联合化疗3个疗程，但胸腔积液仍增多。由于病情进展，其化疗方案改为AUC5卡铂（CBDCA）、200mg/m²紫杉醇（PTX）和15mg/kg贝伐单抗的新联合方案。2个疗程后，胸腔积液显著减少。在初次会诊后的6个月随访期间，病情未加重。
