Fujiwara Ayako, Okami Jiro, Tokunaga Toshiteru, Maeda Jun, Higashiyama Masahiko, Kodama Ken
Department of Thoracic Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1-3-3 Nakamichi, Higashinari, Osaka, 537-8511, Japan.
Gen Thorac Cardiovasc Surg. 2011 Nov;59(11):748-52. doi: 10.1007/s11748-011-0811-3. Epub 2011 Nov 15.
Gastrointestinal metastasis is not common in recurrent non-small-cell lung cancer (NSCLC) patients. There is thus limited information on clinical outcome for these patients. This report presents the clinical characteristics and outcomes of patients with gastrointestinal metastasis after pulmonary resection.
The study retrospectively analyzed nine NSCLC patients with gastrointestinal metastases.
Gastrointestinal metastases were observed in the small intestine (n = 4), colon or rectum (n = 4), and stomach (n = 1). All of the patients were symptomatic. The median survival after gastrointestinal recurrence was 10.8 months. Gastrointestinal surgery was performed in five patients, whereas no cancer treatment was indicated in the remaining four patients. Three patients who underwent surgery for a solitary metastasis survived for more than 2 years after surgery with no other recurrence.
Surgical resection of gastrointestinal metastasis is indicated not only for symptom relief but also for providing a potentially long-term survival if the patients are properly selected.
胃肠道转移在复发性非小细胞肺癌(NSCLC)患者中并不常见。因此,关于这些患者临床结局的信息有限。本报告介绍了肺切除术后发生胃肠道转移患者的临床特征和结局。
本研究回顾性分析了9例发生胃肠道转移的NSCLC患者。
胃肠道转移见于小肠(n = 4)、结肠或直肠(n = 4)以及胃(n = 1)。所有患者均有症状。胃肠道复发后的中位生存期为10.8个月。5例患者接受了胃肠道手术,其余4例患者未接受癌症治疗。3例因孤立性转移接受手术的患者术后存活超过2年且无其他复发。
对于胃肠道转移,手术切除不仅适用于缓解症状,而且如果患者选择得当,还可能带来长期生存。