一种具有高活性和长效活性的新型化学稳定前列环素类似物的合成。
Synthesis of a new chemically stable prostacyclin analogue with high and long-lasting activity.
作者信息
Iseki K, Kanayama T, Hayasi Y, Shibasaki M
机构信息
Research Center, Mitsubishi Kasei Corporation, Yokohama, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1990 Jun;38(6):1769-71. doi: 10.1248/cpb.38.1769.
PMID:2208396
Abstract
The chemically stable prostacyclin analogue (Z)-4,5-didehydroisocarbacyclin analogue (6) has been synthesized. Compound 6 given intravenously or orally is very potent in inhibiting platelet aggregation.
摘要
化学性质稳定的前列环素类似物（Z）-4,5-二脱氢异卡前列素类似物（6）已被合成。静脉注射或口服化合物6在抑制血小板聚集方面非常有效。
Zotero 插件