Gelderblom A J Hans, van der Rhee Jasper I, Ouwerkerk Jan
Leids Universitair Medisch Centrum, Leiden, the Netherlands.
Ned Tijdschr Geneeskd. 2011;155(45):A3994.
A 41-year-old man with metastases of a gastrointestinal stroma tumour was treated with an angiogenesis inhibitor. He presented with a distinct painful erythematous hyperkeratotic bullous hand-foot skin reaction. This was thought to be caused by the oral angiogenesis inhibitor and resolved after discontinuation of the therapy. This is a known adverse effect of angiogenesis inhibitors and is dose dependent.
