Edrissian G H, Mohammadi M, Kanani A, Afshar A, Hafezi R, Ghorbani M, Gharagozloo A R
School of Public Health, Teheran University of Medical Sciences, Iran.
Bull World Health Organ. 1990;68(4):473-7.
In Iran, microscopic examination of skin scrapings from 2202 individuals with clinically diagnosed cutaneous leishmaniasis (CL) lesions revealed the presence of amastigotes in 1123 cases (51.0%). Bacteriological examinations of the lesions indicated that 788 individuals (35.7%) were also infected with one or more pathogenic bacteria, including coagulase-positive staphylococci (27.8%), beta-haemolytic streptococci (10.6%), and other opportunist pathogenic bacteria (total, 2.5%). The prevalence of bacterial infections in lesions in which leishmania parasites were detected was 26.5%, while for lesions in which no parasite was found the prevalence of such infections was significantly greater (45%). The results of this study show that bacterial infections should be considered in diagnosing and treating suspected CL lesions, particularly in areas where there is no facility for carrying out bacteriological examinations. Erythromycin can be used to treat the bacterial infections of the purulent sores.
在伊朗，对2202例临床诊断为皮肤利什曼病（CL）病变的患者进行皮肤刮片显微镜检查发现，1123例（51.0%）存在无鞭毛体。对病变进行的细菌学检查表明，788例（35.7%）还感染了一种或多种病原菌，包括凝固酶阳性葡萄球菌（27.8%）、β溶血性链球菌（10.6%）和其他机会性病原菌（总计2.5%）。在检测到利什曼原虫寄生虫的病变中，细菌感染的患病率为26.5%，而在未发现寄生虫的病变中，此类感染的患病率显著更高（45%）。本研究结果表明，在诊断和治疗疑似CL病变时应考虑细菌感染，尤其是在没有进行细菌学检查设施的地区。红霉素可用于治疗脓性溃疡的细菌感染。
