Department of Materials Molecular Science, Institute for Molecular Science, National Institutes of Natural Sciences, Okazaki, Japan.
Nat Commun. 2011 Nov 15;2:536. doi: 10.1038/ncomms1542.
Covalent organic frameworks (COFs) are a class of important porous materials that allow atomically precise integration of building blocks to achieve pre-designable pore size and geometry; however, pore surface engineering in COFs remains challenging. Here we introduce pore surface engineering to COF chemistry, which allows the controlled functionalization of COF pore walls with organic groups. This functionalization is made possible by the use of azide-appended building blocks for the synthesis of COFs with walls to which a designable content of azide units is anchored. The azide units can then undergo a quantitative click reaction with alkynes to produce pore surfaces with desired groups and preferred densities. The diversity of click reactions performed shows that the protocol is compatible with the development of various specific surfaces in COFs. Therefore, this methodology constitutes a step in the pore surface engineering of COFs to realize pre-designed compositions, components and functions.
共价有机框架（COFs）是一类重要的多孔材料，允许原子精确地集成构建块，以实现可预先设计的孔径和几何形状；然而，COFs 的孔表面工程仍然具有挑战性。在这里，我们将孔表面工程引入 COF 化学中，允许用有机基团对 COF 孔壁进行受控的功能化。通过使用带有叠氮化物的构建块，可以将叠氮化物单元的设计含量锚定在 COF 壁上，从而实现这种功能化。然后，叠氮化物单元可以与炔烃发生定量点击反应，在孔表面上生成具有所需基团和优选密度的基团。所进行的点击反应的多样性表明，该方案与 COFs 中各种特定表面的开发是兼容的。因此，该方法构成了 COFs 孔表面工程中的一个步骤，以实现预先设计的组成、成分和功能。
