Verstraete Frank J M, Zin Bliss P, Kass Philip H, Cox Darren P, Jordan Richard C
Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, CA 95616, USA.
J Am Vet Med Assoc. 2011 Dec 1;239(11):1470-6. doi: 10.2460/javma.239.11.1470.
To characterize clinical signs and histologic findings in dogs with odontogenic cysts and determine whether histologic findings were associated with clinical features.
Retrospective case series.
41 dogs.
Medical records were reviewed to obtain clinical data, including breed, age, sex, and lesion location. Microscopic sections and results of diagnostic imaging were reviewed.
Odontogenic cysts were identified in 41 dogs between 1995 and 2010. There were 29 dogs with dentigerous cysts, 1 with a radicular cyst, 1 with a lateral periodontal cyst, and 1 with a gingival inclusion cyst. In addition, 9 dogs with odontogenic cysts that had clinical and histologic features suggestive of, but not diagnostic for, odontogenic keratocysts seen in people were identified. In all 9 dogs, these cysts were located in the maxilla and surrounded the roots of normally erupted teeth. Of the 29 dogs with dentigerous cysts, 23 had a single cyst, 5 had 2 cysts, and 1 had 3 cysts. Six cysts were associated with an unerupted canine tooth, and 30 were associated with an unerupted first premolar tooth (1 cyst was associated both with an unerupted canine tooth and with an unerupted first premolar tooth). Dentigerous cysts were identified in a variety of breeds, but several brachycephalic breeds were overrepresented, compared with the hospital population during the study period.
Results suggested that a variety of odontogenic cysts can occur in dogs. In addition, cysts that resembled odontogenic keratocysts reported in people were identified. We propose the term canine odontogenic parakeratinized cyst for this condition.
描述牙源性囊肿犬的临床体征和组织学发现，并确定组织学发现是否与临床特征相关。
回顾性病例系列研究。
41只犬。
查阅病历以获取临床数据，包括品种、年龄、性别和病变位置。回顾显微镜切片和诊断性影像学检查结果。
在1995年至2010年间，41只犬被确诊患有牙源性囊肿。其中含牙囊肿29只，根囊肿1只，侧方牙周囊肿1只，牙龈包涵囊肿1只。此外，还发现9只患有牙源性囊肿的犬，其临床和组织学特征提示为人所见的牙源性角化囊肿，但不能确诊。所有9只犬的这些囊肿均位于上颌骨，围绕正常萌出牙齿的牙根。在29只含牙囊肿犬中，23只患有单个囊肿，5只患有2个囊肿，1只患有3个囊肿。6个囊肿与未萌出的犬齿相关，30个囊肿与未萌出的第一前磨牙相关（1个囊肿与未萌出的犬齿和未萌出的第一前磨牙均相关）。含牙囊肿在多种品种的犬中均有发现，但与研究期间医院的犬类种群相比，几种短头品种的犬比例过高。
结果表明犬可发生多种牙源性囊肿。此外，还发现了与人报道的牙源性角化囊肿相似的囊肿。我们建议将这种情况称为犬牙源性不全角化囊肿。
