TREAT：一个用于靶向和外显子组测序数据中变异注释和可视化的生物信息学工具。
TREAT: a bioinformatics tool for variant annotations and visualizations in targeted and exome sequencing data.
机构信息
Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo College of Medicine, Rochester, MN, USA.
出版信息
Bioinformatics. 2012 Jan 15;28(2):277-8. doi: 10.1093/bioinformatics/btr612. Epub 2011 Nov 15.
Abstract
UNLABELLED
TREAT (Targeted RE-sequencing Annotation Tool) is a tool for facile navigation and mining of the variants from both targeted resequencing and whole exome sequencing. It provides a rich integration of publicly available as well as in-house developed annotations and visualizations for variants, variant-hosting genes and host-gene pathways.
AVAILABILITY AND IMPLEMENTATION
TREAT is freely available to non-commercial users as either a stand-alone annotation and visualization tool, or as a comprehensive workflow integrating sequencing alignment and variant calling. The executables, instructions and the Amazon Cloud Images of TREAT can be downloaded at the website: http://ndc.mayo.edu/mayo/research/biostat/stand-alone-packages.cfm.
摘要
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TREAT（靶向重测序注释工具）是一种用于方便导航和挖掘靶向重测序和全外显子组测序中变体的工具。它为变体、变体宿主基因和宿主基因途径提供了丰富的公共可用注释和可视化集成，以及内部开发的注释和可视化集成。
可用性和实现
TREAT 可作为独立的注释和可视化工具，或作为一个综合工作流程，将测序比对和变异调用集成在一起，免费提供给非商业用户使用。TREAT 的可执行文件、说明和亚马逊云映像可以在以下网站下载：http://ndc.mayo.edu/mayo/research/biostat/stand-alone-packages.cfm。
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