Hötzinger H, Salbeck R, Toedt C, Beyer H K
Marienhospital I, Abteilung für Kernspintomographie, Ruhruniversität Bochum.
Digitale Bilddiagn. 1990 Jun;10(2):42-5.
The use of an oral contrast medium has so far not become a matter of routine in MR of the abdomen. In the present study the use of orally applied gadolinium-DTPA was examined in respect of tumorous diseases in the minor pelvis. 18 patients with tumours in the minor pelvis were examined before and after oral administration of gadolinium-DTPA (Gd-DTPA). 10 ml/kg body weight of a gadolinium DTPA solution were applied in a concentration of 1.0 mmol/l. T1-weighted and T2-weighted sequences were carried out before application and T1-weighted sequences after application. Oral application gadolinium-DTPA resulted in enhancing the signals of the filled intestinal portions. In 54% of the cases the sequences showed a sharper delineation between tumour and intestine. In 19% the delineation between pathological tissue and intestine on contrast examination was as well defined as in T2-weighted contrast images; in 27% of the cases oral administration of gadolinium-DTPA did not yield any additional information. No significant side effects were seen.
迄今为止,口服造影剂在腹部磁共振成像中尚未成为常规应用。在本研究中,针对盆腔内肿瘤性疾病,对口服钆喷酸葡胺的应用进行了研究。18例盆腔肿瘤患者在口服钆喷酸葡胺(Gd-DTPA)前后接受了检查。以1.0 mmol/l的浓度应用10 ml/kg体重的钆喷酸葡胺溶液。在应用前进行T1加权和T2加权序列成像,应用后进行T1加权序列成像。口服钆喷酸葡胺使充盈的肠段信号增强。在54%的病例中,序列显示肿瘤与肠之间的界限更清晰。在19%的病例中,对比检查时病理组织与肠之间的界限与T2加权对比图像中一样清晰;在27%的病例中,口服钆喷酸葡胺未提供任何额外信息。未观察到明显的副作用。