Department of Family Medicine and Department of Anesthesia, McGill University, Montreal, Quebec, Canada.
Clin Pharmacol Ther. 2011 Dec;90(6):769-71. doi: 10.1038/clpt.2011.241.
The hazy world of "medical marijuana" continues to cry out for clear data on which to base medical decision making and rational policy design. In this issue of Clinical Pharmacology & Therapeutics, Abrams and colleagues report that vaporized cannabis does not meaningfully affect opioid plasma levels and may even augment the efficacy of oxycodone and morphine in patients with chronic non-cancer pain. This Commentary considers the implications of this work for clinical practice and further research initiatives.
在“医用大麻”这个模糊不清的领域，仍然迫切需要清晰的数据来为医疗决策和合理的政策设计提供依据。在本期《临床药理学与治疗学》杂志上，Abrams 及其同事报告称，汽化大麻不会显著影响阿片类药物的血浆水平，甚至可能增强慢性非癌痛患者使用羟考酮和吗啡的疗效。本文述评探讨了这项工作对临床实践和进一步研究计划的意义。
