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冠状动脉 CT 血管造影或应激试验与医疗保险受益人的后续利用和支出的关联。

Association of coronary CT angiography or stress testing with subsequent utilization and spending among Medicare beneficiaries.

机构信息

Stanford University School of Medicine, Stanford, CA 94305-5405, USA.

出版信息

JAMA. 2011 Nov 16;306(19):2128-36. doi: 10.1001/jama.2011.1652.

Abstract

CONTEXT

Coronary computed tomography angiography (CCTA) is a new noninvasive diagnostic test for coronary artery disease (CAD), but its association with subsequent clinical management has not been established.

OBJECTIVE

To compare utilization and spending associated with functional (stress testing) and anatomical (CCTA) noninvasive cardiac testing in a Medicare population.

DESIGN, SETTING, AND PATIENTS: Retrospective, observational cohort study using claims data from a 20% random sample of 2005-2008 Medicare fee-for-service beneficiaries 66 years or older with no claims for CAD in the preceding year, who received nonemergent, noninvasive testing for CAD (n = 282,830).

MAIN OUTCOME MEASURES

Cardiac catheterization, coronary revascularization, acute myocardial infarction, all-cause mortality, and total and CAD-related Medicare spending over 180 days of follow-up.

RESULTS

Compared with stress myocardial perfusion scintigraphy (MPS), CCTA was associated with an increased likelihood of subsequent cardiac catheterization (22.9% vs 12.1%; adjusted odds ratio [AOR], 2.19 [95% CI, 2.08 to 2.32]; P < .001), percutaneous coronary intervention (7.8% vs 3.4%; AOR, 2.49 [2.28 to 2.72]; P < .001), and coronary artery bypass graft surgery (3.7% vs 1.3%; AOR, 3.00 [2.63 to 3.41]; P < .001). CCTA was also associated with higher total health care spending ($4200 [$3193 to $5267]; P < .001), which was almost entirely attributable to payments for any claims for CAD ($4007 [$3256 to $4835]; P < .001). Compared with MPS, there was lower associated spending with stress echocardiography (-$4981 [-$4991 to -$4969]; P < .001) and exercise electrocardiography (-$7449 [-$7452 to -$7444]; P < .001). At 180 days, CCTA was associated with a similar likelihood of all-cause mortality (1.05% vs 1.28%; AOR, 1.11 [0.88 to 1.38]; P = .32) and a slightly lower likelihood of hospitalization for acute myocardial infarction (0.19% vs 0.43%; AOR, 0.60 [0.37 to 0.98]; P = .04).

CONCLUSION

Medicare beneficiaries who underwent CCTA in a nonacute setting were more likely to undergo subsequent invasive cardiac procedures and have higher CAD-related spending than patients who underwent stress testing.

摘要

背景

冠状动脉计算机断层血管造影(CCTA)是一种新的非侵入性诊断冠状动脉疾病(CAD)的方法,但它与随后的临床管理的关系尚未确定。

目的

比较在 Medicare 人群中,功能(应激测试)和解剖(CCTA)非侵入性心脏测试的使用情况和费用。

设计、设置和患者:使用来自 2005-2008 年 Medicare 按服务收费受益人的 20%随机样本的索赔数据进行回顾性观察队列研究,这些患者年龄在 66 岁或以上,在前一年没有 CAD 的索赔,并且接受了非紧急、非侵入性 CAD 测试(n=282830)。

主要观察指标

心脏导管检查、冠状动脉血运重建、急性心肌梗死、全因死亡率以及在 180 天随访期间的总和 CAD 相关 Medicare 支出。

结果

与应激心肌灌注闪烁扫描(MPS)相比,CCTA 与随后进行心脏导管检查的可能性增加相关(22.9% vs 12.1%;调整后的优势比[OR],2.19 [95%CI,2.08 至 2.32];P<0.001)、经皮冠状动脉介入治疗(7.8% vs 3.4%;OR,2.49 [2.28 至 2.72];P<0.001)和冠状动脉旁路移植术(3.7% vs 1.3%;OR,3.00 [2.63 至 3.41];P<0.001)。CCTA 还与更高的总医疗保健支出相关($4200 [$3193 至 $5267];P<0.001),这几乎完全归因于任何 CAD 索赔的支付($4007 [$3256 至 $4835];P<0.001)。与 MPS 相比,应激超声心动图(-$4981 [-$4991 至 -$4969];P<0.001)和运动心电图(-$7449 [-$7452 至 -$7444];P<0.001)的相关支出较低。在 180 天,CCTA 与全因死亡率(1.05% vs 1.28%;OR,1.11 [0.88 至 1.38];P=0.32)的可能性相似,并且急性心肌梗死的住院率略低(0.19% vs 0.43%;OR,0.60 [0.37 至 0.98];P=0.04)。

结论

在非急性情况下接受 CCTA 的 Medicare 受益人的后续侵入性心脏手术可能性更高,并且与接受应激测试的患者相比,CAD 相关支出更高。

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