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韩国医保索赔数据揭示经皮冠状动脉介入治疗后随访策略的医院间差异。

Hospital-level variation in follow-up strategies after percutaneous coronary intervention, revealed in health claims data of Korea.

机构信息

Department of Cardiology in Internal Medicine, School of Medicine, Cardiovascular Center, Chungnam National University, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, Korea.

Department of Internal Medicine, Kyungpook National University School of Medicine, Cardiology Center, Kyungpook National University Chilgok Hospital, Daegu, Korea.

出版信息

Sci Rep. 2021 Feb 8;11(1):3322. doi: 10.1038/s41598-021-82960-4.

Abstract

This study sought to determine hospital variation in the use of follow-up stress testing (FUST) and invasive coronary angiography (FUCAG) after percutaneous coronary intervention (PCI). The claims records of 150,580 Korean patients who received PCI in 128 hospitals between 2008 and 2015 were analyzed. Patient were considered to have undergone FUST and FUCAG, when these testings were performed within two years after discharge from the index hospitalization. Hierarchical generalized linear and frailty models were used to evaluate binary and time-to-event outcomes. Hospital-level risk-standardized FUCAG and FUST rates were highly variable across the hospitals (median, 0.41; interquartile range [IQR], 0.27-0.59; median, 0.22; IQR, 0.08-0.39, respectively). The performances of various models predicting the likelihood of FUCAG and FUST were compared, and the best performance was observed with the models adjusted for patient case mix and individual hospital effects as random effects (receiver operating characteristic curves, 0.72 for FUCAG; 0.82 for FUST). The intraclass correlation coefficients of the models (0.41 and 0.68, respectively) indicated that a considerable proportion of the observed variation was related to individual institutional effects. Higher hospital-level FUCAG and FUST rates were not preventive of death or myocardial infarction. Increased repeat revascularizations were observed in hospitals with higher FUCAG rates.

摘要

本研究旨在确定经皮冠状动脉介入治疗(PCI)后,医院在使用随访应激试验(FUST)和有创冠状动脉造影(FUCAG)方面的差异。分析了 2008 年至 2015 年间 128 家医院 150580 名接受 PCI 的韩国患者的索赔记录。当这些检查在索引住院出院后两年内进行时,患者被认为接受了 FUST 和 FUCAG。使用分层广义线性和脆弱性模型评估二项式和时间事件结果。医院层面风险标准化的 FUCAG 和 FUST 率在医院之间差异很大(中位数,0.41;四分位距 [IQR],0.27-0.59;中位数,0.22;IQR,0.08-0.39)。比较了预测 FUCAG 和 FUST 可能性的各种模型的表现,发现调整患者病例组合和个体医院效应作为随机效应的模型表现最佳(接收者操作特征曲线,FUCAG 为 0.72;FUST 为 0.82)。模型的组内相关系数(0.41 和 0.68)表明,观察到的差异中有相当一部分与个体机构效应有关。较高的医院层面 FUCAG 和 FUST 率并不能预防死亡或心肌梗死。在 FUCAG 率较高的医院中观察到更多的重复血运重建。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0736/7870879/fcb89d0cd769/41598_2021_82960_Fig1_HTML.jpg

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