Niafar Mitra, Dabiri Shahram, Bozorgi Farshid, Niafar Farid, Gholami Nasrin
Assistant Professor, Endocrinology and Metabolism Section, Department of Medicine, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
J Res Med Sci. 2011 Apr;16(4):568-73.
Medullary thyroid carcinoma accounts for 4% of thyroid carcinoma and originates from parafollicular cells, secreting calcitonin and carcinoembryonic antigen (CEA). Conventional radiographic modalities such as Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), and Ultrasonography (U/S), are used for detecting recurrences following total thyroidectomy. However, metastatic disease frequently escapes detection by the above modalities, even when its presence is suggested by persistently elevated serum calcitonin levels. In this paper, we report a case of medullary thyroid carcinoma in a 40 year-old woman who had whole body octreotide scintigraphy to evaluate and detect the origin of calcitonin and CEA secretion.
甲状腺髓样癌占甲状腺癌的4%，起源于滤泡旁细胞，分泌降钙素和癌胚抗原（CEA）。传统的影像学检查方法，如计算机断层扫描（CT）、磁共振成像（MRI）和超声检查（U/S），用于检测甲状腺全切除术后的复发情况。然而，即使血清降钙素水平持续升高提示转移灶的存在，转移病灶仍常无法通过上述检查方法被发现。在本文中，我们报告了一例40岁女性甲状腺髓样癌患者，该患者接受了全身奥曲肽闪烁扫描，以评估和检测降钙素及CEA分泌的来源。
