[Outcome of pregnancy complicated by hepatitis A in the urban districts of Shanghai].

In 1988, during an epidemic 431 cases of hepatitis A among a group 7,476 pregnant women were in the 12 Women Health Units at urban area of Shanghai, accounting for a morbidity rate of 5,765.1/100,000 pregnant women. The ratio of spontaneous abortion, induced abortion and term delivery were 18:15:67. There were 16 perinatal deaths in the 288 delivered cases. The perinatal mortality rate was 55.6/1,000 and its relative risk, as compared with that of the whole Shanghai Urban Districts was 4.1, at the same time, 83 cases of pregnancies associated with Hepatitis A (all confirmed by anti-hepatitis A Virus IgM assay) were studied in detail in the Shanghai Municipal Women Health Institute. The average birth weight of the new born was slightly lower and the mortality rate was significantly higher than those in a control group of 168 cases, there was no fetal infection as evidenced by fetal blood anti HAV IgM.