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人输精管上皮细胞中的核内包涵体。

Intranuclear inclusion bodies in epithelial cells of human vas deferens.

作者信息

Chakraborty J, Nelson L, Jhunjhunwala J, Young M, Kropp K

出版信息

Arch Androl. 1979;2(1):1-12. doi: 10.3109/01485017908987285.

DOI:10.3109/01485017908987285
PMID:220924
Abstract

Four different types of inclusion bodies were seen within the nucleus of the principal cells in segments of vas deferens from 40 fertile males: (1) electron-dense homogeneous bodies of various sizes (0.1--1.8 microns) and shapes, (2) granular bodies approximately 0.06--0.12 microns, (3) lipid inclusion bodies, and (4) less electron-dense, filamentous bodies. They were either membrane-bound or free within the nucleoplasm. Some membranous material was scattered within the nucleoplasm. The internal structure of nuclei containing these bodies differed from cell to cell. The nucleoplasm was composed either of dense granular elements or fine filamentous components. The aggregation and density of the ground nuclear material increased with increasing numbers of inclusion bodies. Very dense nuclei were in cells with typical features of degeneration. Frequently, extruded parts of cells or entire cells were seen within the lumen of the vas deferens.

摘要

在40名生育期男性输精管各段主细胞的细胞核内可见四种不同类型的包涵体:(1)各种大小(0.1 - 1.8微米)和形状的电子致密均质体,(2)直径约0.06 - 0.12微米的颗粒体,(3)脂质包涵体,以及(4)电子密度较低的丝状物体。它们要么被膜包裹,要么游离于核质中。一些膜状物质散布在核质内。含有这些包涵体的细胞核内部结构因细胞而异。核质要么由致密的颗粒成分组成,要么由细丝状成分组成。随着包涵体数量的增加,核基质材料的聚集和密度也增加。细胞核非常致密的细胞具有典型的退化特征。在输精管腔内经常可见细胞的挤出部分或整个细胞。

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