Department of Urology, Medical University of Graz, Graz, Austria.
BJU Int. 2012 Aug;110(3):363-8. doi: 10.1111/j.1464-410X.2011.10765.x. Epub 2011 Nov 17.
• To analyse the overall accuracy of Partin tables, with special emphasis to potential limitations resulting from differences between prostate cancers detected by different biopsy schedules.
• Clinical characteristics from 599 patients treated with radical prostatectomy defined the 2007 Partin probabilities of organ confinement (OC), seminal vesicle invasion (SVI) and extracapsular extension (ECE). Prostate cancers were detected by initial biopsy (IBx) with ≤12 cores in 405 patients (67.6%), by conventional repeat biopsy (CRBx) with ≤12 cores in 99 (16.5%) and by saturation repeat biopsy (SRBx) with ≥20 cores in 95 patients (15.9%). • The area under the curve (AUC) estimated by the receiver operating characteristic curve, assessed the predictive accuracy of the 2007 Partin tables.
• The Partin tables AUC of the IBx, CRBx and the SRBx groups were 0.730 vs 0.701 vs 0.585 for OC, 0.631 vs 0.689 vs 0.547 for ECE, and 0.775 vs 0.755 vs 0.641 for SVI, respectively.
• The overall accuracy of the 2007 Partin tables was clearly inferior in patients with prostate cancers detected by SRBx. • Prostate cancers detected by SRBx undermine the Partin tables' overall accuracy, and this group of patients may be miscounselled by vague predictions.
• 分析 Partin 表的整体准确性，特别强调由于不同活检方案检测到的前列腺癌之间的差异而导致的潜在局限性。
• 599 例接受根治性前列腺切除术治疗的患者的临床特征定义了 2007 年 Partin 对器官局限性（OC）、精囊侵犯（SVI）和包膜外扩展（ECE）的概率。前列腺癌通过初始活检（IBx）在 405 例患者中检测（≤12 个核心），在 99 例患者中通过常规重复活检（CRBx）检测（≤12 个核心），在 95 例患者中通过饱和重复活检（SRBx）检测（≥20 个核心）。• 受试者工作特征曲线（ROC）估计的曲线下面积（AUC）评估了 2007 年 Partin 表的预测准确性。
• IBx、CRBx 和 SRBx 组的 Partin 表 AUC 分别为 OC 的 0.730 对 0.701 对 0.585，ECE 的 0.631 对 0.689 对 0.547，SVI 的 0.775 对 0.755 对 0.641。
• 2007 年 Partin 表在通过 SRBx 检测到的前列腺癌患者中的整体准确性明显较差。• 通过 SRBx 检测到的前列腺癌削弱了 Partin 表的整体准确性，这组患者可能会因模糊的预测而被误诊。
