Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Songpagu, Seoul, Korea.
Dermatol Surg. 2012 Jan;38(1):68-76. doi: 10.1111/j.1524-4725.2011.02149.x. Epub 2011 Sep 7.
Combined optical and bipolar radiofrequency (RF) devices have been effective for rejuvenation, but a single modality in one session cannot solve three-dimensional skin complaints, resulting in time-consuming visits.
To evaluate the safety and efficacy of single-session triple treatment using bipolar RF-based optical (intense pulsed light [IPL], infrared light, and diode laser) combination devices for treatment of photoaged Asian skin.
In a split-face trial, 11 women received four treatments at 3-week intervals consisting of the combination of sequential IPL, infrared light, and diode laser, all with RF, in one session. Outcome assessments included photography, global evaluation by blinded investigators, patient assessment, and objective biophysical measurements of color and elasticity. Punch biopsies were obtained from both sides of the face 1 month after the last treatment session.
All patients showed statistically significant reduction in photoaging global score. Objective biophysical measurements showed significant improvements in melanin index and elasticity (R5, R7), as well as increases in the levels of procollagen type I and III and elastin.
A combination of three different energy sources, with bipolar RF, in one session is effective without further downtime for solving multiple problems including tone, texture, and laxity observed in photoaged Asian skin.
联合使用光学和双极射频 (RF) 设备可有效实现皮肤年轻化，但单次治疗的单一模式无法解决三维皮肤问题，导致治疗需要多次就诊，耗时较长。
评估单次三治疗疗程中使用基于双极 RF 的光学（强脉冲光 [IPL]、红外光和二极管激光）组合设备治疗亚洲人光老化皮肤的安全性和疗效。
在一项分面试验中，11 名女性接受了四次治疗，每 3 周间隔一次，治疗方案为 IPL、红外光和二极管激光的顺序组合，均联合 RF 治疗，所有治疗均在一次疗程中完成。疗效评估包括拍照、盲法研究者的整体评估、患者评估以及肤色和弹性的客观生物物理测量。末次治疗后 1 个月，从面部两侧取活检。
所有患者的光老化整体评分均有统计学显著降低。客观生物物理测量显示黑色素指数和弹性（R5、R7）显著改善，I 型和 III 型前胶原以及弹性蛋白水平增加。
单次治疗中联合使用三种不同的能量源（双极 RF），无需额外停机时间，即可有效解决亚洲人光老化皮肤中观察到的肤色、质地和松弛等多种问题。
