Department of Laboratory Medicine, University of Padova, Italy.
Am J Clin Pathol. 2011 Dec;136(6):829-33. doi: 10.1309/AJCPR28HWHSSDNON.
Forty years ago, Lundberg introduced the concept of the brain-to-brain loop for laboratory testing. In this concept, in the brain of the physician caring for the patient, the first step involves the selection of laboratory tests and the final step is the transmission of the test result to the ordering physician. There are many intermediary steps, some of which are preanalytic, ie, before performance of the test; some are analytic and relate to the actual performance of the test; and others are postanalytic and involve transmission of test results into the medical record. The introduction of this concept led to a system to identify and classify errors associated with laboratory test performance. Errors have since been considered as preanalytic, analytic, and postanalytic. During the past 4 decades, changes in medical practice have significantly altered the brain-to-brain loop for laboratory testing. This review describes the changes and their implications for analysis of errors associated with laboratory testing.
四十年前，Lundberg 提出了脑对脑循环的概念，用于实验室检测。在这个概念中，负责照顾患者的医生的大脑中，第一步涉及选择实验室检测，最后一步是将检测结果传输给开单医生。这中间有许多步骤，有些是分析前的，即在进行检测之前；有些是分析中的，与实际进行的检测有关；还有些是分析后的，涉及将检测结果传输到病历中。这一概念的引入导致了一种识别和分类与实验室检测性能相关的错误的系统。此后，错误被认为是分析前、分析中和分析后的。在过去的四十年中，医疗实践的变化极大地改变了用于实验室检测的脑对脑循环。这篇综述描述了这些变化及其对与实验室检测相关的错误分析的影响。
