State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, PR China.
Environ Toxicol Chem. 2012 Feb;31(2):289-95. doi: 10.1002/etc.749. Epub 2011 Dec 29.
Biodegradation of the ultraviolet (UV) filter benzophenone-3 (BP-3) was investigated in the laboratory to understand its behavior and fate under oxic and anoxic (nitrate, sulfate, and Fe [III]-reducing) conditions. Biodegradation experiments were conducted in microcosms with 10% of activated sludge and digested sludge under oxic and anoxic conditions, respectively. Benzophenone-3 was well degraded by microorganisms under each redox condition. Under the redox conditions studied, the biodegradation half-life for BP-3 had the following order: oxic (10.7 d) > nitrate-reducing (8.7 d) > Fe (III)-reducing (5.1 d) > sulfate-reducing (4.3 d) ≥ anoxic unamended (4.2 d). The results suggest that anaerobic biodegradation is a more favorable attenuation mechanism for BP-3. Biodegradation of BP-3 produced two products, 4-cresol and 2,4-dihydroxybenzophenone, under oxic and anoxic conditions. Biotransformation of BP-3 to 2,4-dihydroxybenzophenone by way of demethylation of the methoxy substituent (O-demethylation) occurred in cultures under each redox condition. The further biotransformation of 2,4-dihydroxybenzophenone to 4-cresol was inhibited under oxic, nitrate-reducing, and sulfate-reducing conditions.
研究了紫外线（UV）过滤器二苯甲酮-3（BP-3）的生物降解，以了解其在好氧和缺氧（硝酸盐、硫酸盐和三价铁还原）条件下的行为和归宿。在微宇宙中进行了生物降解实验，分别在好氧和缺氧条件下使用 10%的活性污泥和消化污泥。BP-3 在每种氧化还原条件下都被微生物很好地降解。在研究的氧化还原条件下，BP-3 的生物降解半衰期顺序如下：好氧（10.7d）>硝酸盐还原（8.7d）>三价铁还原（5.1d）>硫酸盐还原（4.3d）≥缺氧未添加（4.2d）。结果表明，厌氧生物降解是 BP-3 的更有利的衰减机制。BP-3 的生物降解在好氧和缺氧条件下产生了两种产物，4- 甲基苯酚和 2,4-二羟基二苯甲酮。在每种氧化还原条件下的培养物中，BP-3 通过甲氧基取代基的脱甲基（O-脱甲基化）转化为 2,4-二羟基二苯甲酮。在好氧、硝酸盐还原和硫酸盐还原条件下，2,4-二羟基二苯甲酮进一步转化为 4-甲基苯酚受到抑制。
