Roca M, Iosep G, Mihăescu T
Spitalul Clinic de Pneumoftiziologie, Iaşi.
Pneumologia. 2011 Jul-Sep;60(3):147-9.
To describe the characteristics of patients with tuberculosis (TB) requiring intensive care and to identify the risk factors for mortality.
We conducted a retrospective, cohort study, between January 2006 and December 2009. The patients with TB, admitted in Pneumology Clinic Hospital, Iasi, requiring advanced life support in intensive care unit (ICU), were included. We assessed different clinical parameters to identify the factors that predict in-hospital mortality. The primary outcome was the in-hospital mortality.
During the study period, 27 patients with TB required intensive care. Of them, 16 (59.3%) had acute respiratory failure and 6 (22.2%) required mechanical ventilation. Eighteen (66.7%) patients died. Acute respiratory failure, acute hepatic failure and mechanical ventilation significantly correlate with a high in-hospital mortality rate.
In this study we found a high mortality rate in TB patients requiring intensive care, identifying some risk factors.
描述需要重症监护的结核病（TB）患者的特征，并确定死亡风险因素。
我们在2006年1月至2009年12月期间进行了一项回顾性队列研究。纳入在雅西肺病专科医院就诊、需要在重症监护病房（ICU）接受高级生命支持的结核病患者。我们评估了不同的临床参数，以确定预测院内死亡率的因素。主要结局是院内死亡率。
在研究期间，27例结核病患者需要重症监护。其中，16例（59.3%）发生急性呼吸衰竭，6例（22.2%）需要机械通气。18例（66.7%）患者死亡。急性呼吸衰竭、急性肝衰竭和机械通气与高院内死亡率显著相关。
在本研究中，我们发现需要重症监护的结核病患者死亡率很高，并确定了一些风险因素。
