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术前预测输精管复通术中需要行附睾输精管吻合术概率的列线图。

Nomogram to preoperatively predict the probability of requiring epididymovasostomy during vasectomy reversal.

机构信息

Cheseapeake Urology Associates, Baltimore, Maryland 20759, USA.

出版信息

J Urol. 2012 Jan;187(1):215-8. doi: 10.1016/j.juro.2011.09.026. Epub 2011 Nov 17.

Abstract

PURPOSE

Up to 6% of men who undergo vasectomy may later undergo vasectomy reversal. Most men require vasovasostomy but a smaller subset requires epididymovasostomy. Outcomes of epididymovasostomy depend highly on specialized training in microsurgery and, if predicted preoperatively, might warrant referral to a specialist in this field. We created a nomogram based on preoperative patient characteristics to better predict the need for epididymovasostomy.

MATERIALS AND METHODS

We evaluated patients who underwent primary vasectomy reversal during a 5-year period. Preoperative and intraoperative patient data were collected in a prospectively maintained database. We evaluated the ability of age, years since vasectomy, vasectomy site, epididymal fullness and granuloma presence or absence to preoperatively predict the need for epididymovasostomy in a given patient. The step-down method was used to create a parsimonious model, on which a nomogram was created and assessed for predictive accuracy.

RESULTS

Included in the study were 271 patients with a mean age of 42 years. Patient age was not positively associated with epididymovasostomy. Mean time from vasectomy to reversal was 9.7 years. Time to reversal and a sperm granuloma were selected as important predictors of epididymovasostomy in the final parsimonious model. The nomogram achieved a bias corrected concordance index of 0.74 and it was well calibrated.

CONCLUSIONS

Epididymovasostomy can be preoperatively predicted based on years since vasectomy and a granuloma on physical examination. Urologists can use this nomogram to better inform patients of the potential need for epididymovasostomy and whether specialist referral is needed.

摘要

目的

接受输精管结扎术的男性中,多达 6%可能会在以后进行输精管吻合术。大多数男性需要进行输精管吻合术,但一小部分需要进行附睾输精管吻合术。附睾输精管吻合术的结果高度依赖于显微外科的专业培训,如果术前预测到,可能需要转介给该领域的专家。我们创建了一个基于术前患者特征的列线图,以更好地预测需要进行附睾输精管吻合术的情况。

材料和方法

我们评估了在 5 年期间接受初次输精管吻合术的患者。在一个前瞻性维护的数据库中收集了术前和术中患者数据。我们评估了年龄、输精管结扎术后时间、结扎部位、附睾饱满程度以及肉芽肿的存在或缺失,以预测在特定患者中是否需要进行附睾输精管吻合术。采用逐步降阶法创建一个简约模型,在此基础上创建并评估列线图的预测准确性。

结果

研究纳入了 271 名平均年龄为 42 岁的患者。患者年龄与附睾输精管吻合术无明显相关性。输精管结扎术到吻合术的平均时间为 9.7 年。时间到逆转和精子肉芽肿被选为最终简约模型中附睾输精管吻合术的重要预测因素。该列线图的校正后一致性指数为 0.74,具有良好的校准度。

结论

可以根据输精管结扎术后时间和体格检查中的肉芽肿来预测附睾输精管吻合术。泌尿科医生可以使用该列线图更好地告知患者潜在的附睾输精管吻合术需求以及是否需要专家转诊。

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