Department of Surgery, Leiden University Medical Centre, P.O. box 9600, 2300 RC Leiden, The Netherlands.
J Tissue Viability. 2012 Feb;21(1):13-6. doi: 10.1016/j.jtv.2011.10.002. Epub 2011 Nov 18.
Necrotizing fasciitis is a serious disease entity, with only limited pathognomic features.
In necrotizing fasciitis a rapid diagnosis is necessary in order to reduce morbidity and mortality. In this study the investigation focused on specific features in the frozen section biopsy for diagnosing necrotizing fasciitis.
A total of ten patients are described with final pathological examination of resected tissue.
A new grading system is suggested for frozen section biopsy in patients with necrotizing fasciitis. In the herein reported study it was found that granulocytes were present in both the frozen section biopsy and in the definitive paraffin coupes, in the subcutis and fascia layer.
Frozen section biopsy could be useful in diagnosing necrotizing fasciitis.
坏死性筋膜炎是一种严重的疾病实体，只有有限的特征。
坏死性筋膜炎需要快速诊断，以降低发病率和死亡率。本研究的重点是在冷冻切片活检中诊断坏死性筋膜炎的具体特征。
共描述了 10 例患者，最终通过切除组织的病理检查进行诊断。
建议为坏死性筋膜炎患者的冷冻切片活检建立一个新的分级系统。在本研究中发现，粒细胞存在于冷冻切片活检和明确的石蜡切片中，位于皮下组织和筋膜层。
冷冻切片活检可用于诊断坏死性筋膜炎。
